help button home button
AJRCCM
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by PILLOW, J. J.
Right arrow Articles by RAMSDEN, C. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by PILLOW, J. J.
Right arrow Articles by RAMSDEN, C. A.

Am. J. Respir. Crit. Care Med., Volume 164, Number 6, September 2001, 1019-1024

In Vitro Performance Characteristics of High-Frequency Oscillatory Ventilators

J. JANE PILLOW, MALCOLM H. WILKINSON, HEATHER L. NEIL, and C. ANDREW RAMSDEN

TVW Telethon Institute for Child Health Research, Perth, Australia; Department of Paediatrics, University of Western Australia, Perth, Australia; King Edward & Princess Margaret Hospital, Perth, Australia; Ritchie Center for Baby Health Research, Institute of Reproduction and Development, Monash University, Clayton, Victoria, Australia; and Department of Paediatrics, Monash University, Victoria, Australia

This study aimed to examine the performance characteristics of four high-frequency oscillatory-type ventilators, using an in vitro model of the intubated neonatal respiratory system. Each ventilator was examined across its operative range of settings and at varying model lung compliance (C) and resistance. The oscillatory pressure waveform was measured at the airway opening (Pao). Tidal volume (VT) and flow were determined from pressure changes within the model lung (Delta PA). The spectral content of the Pao waveform differed between ventilators. The maximum ventilator VT ranged from 3.7 to 11.1 ml at 15 Hz and a mean airway pressure (Paw) of 12 cm H2O to oscillate a model lung (C = 0.4 ml/cm H2O) through a 3.0-mm internal diameter (i.d.) endotracheal tube (ETT). A small drop in C was associated with a decrease in VT and marked increase in Delta PA from 0.1 to 0.8 ml/cm H2O. The influence of C on VT and Delta PA and the pressure cost of ventilation (Delta PA/f·VT2) was dependent on the oscillatory frequency, ETT inner diameter, and the specific ventilator used. Substantive differences exist between oscillatory ventilators that need to be considered in their clinical application. The rapid establishment of optimal lung volume and oscillatory frequency is important in minimizing barotrauma during high-frequency oscillatory ventilation.

Keywords: compliance; high-frequency ventilation; newborn; respiratory distress syndrome; ventilator properties




This article has been cited by other articles:


Home page
 Arch. Dis. Child. Fetal Neonatal Ed.Home page
J A Leipala, S Iwasaki, A Milner, and A Greenough
Accuracy of the volume and pressure displays of high frequency oscillators
Arch. Dis. Child. Fetal Neonatal Ed., March 1, 2004; 89(2): F174 - F176.
[Abstract] [Full Text] [PDF]

Home page
 Evid. Based Nurs.Home page
C. Cheng and P. Shah
High frequency oscillatory ventilation was not more effective than conventional ventilation in preterm infants
Evid. Based Nurs., April 1, 2003; 6(2): 41 - 41.
[Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
S. Derdak, S. Mehta, T. E. Stewart, T. Smith, M. Rogers, T. G. Buchman, B. Carlin, S. Lowson, J. Granton, and the Multicenter Oscillatory Ventilation
High-Frequency Oscillatory Ventilation for Acute Respiratory Distress Syndrome in Adults: A Randomized, Controlled Trial
Am. J. Respir. Crit. Care Med., September 15, 2002; 166(6): 801 - 808.
[Abstract] [Full Text]

Home page
 NEJMHome page
A. R. Stark
High-Frequency Oscillatory Ventilation to Prevent Bronchopulmonary Dysplasia -- Are We There Yet?
N. Engl. J. Med., August 29, 2002; 347(9): 682 - 684.
[Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
M. J. TOBIN
Critical Care Medicine in AJRCCM 2001
Am. J. Respir. Crit. Care Med., March 1, 2002; 165(5): 565 - 583.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Proc. Am. Thorac. Soc. Am. J. Respir. Cell Mol. Biol.
Copyright © 2001 American Thoracic Society 		  2009/2010 ATS Fellows Career Development Awards