EDITORIALS:

Marc Humbert and Marius M. Hoeper

Severe Pulmonary Arterial Hypertension: A Forme Fruste of Cancer?

Am. J. Respir. Crit. Care Med. 2008; 178: 551-552 [Full Text] [PDF]  

Peter J. Barnes

Defective Antioxidant Gene Regulation in COPD: A Case for Broccoli

Am. J. Respir. Crit. Care Med. 2008; 178: 552-554 [Full Text] [PDF]  

Gordon D. Rubenfeld and Edward Abraham

When Is a Negative Phase II Trial Truly Negative?

Am. J. Respir. Crit. Care Med. 2008; 178: 554-555 [Full Text] [PDF]  

Anna Hansell

Airborne Environmental Exposure to Asbestos

Am. J. Respir. Crit. Care Med. 2008; 178: 556-557 [Full Text] [PDF]  

PULMONARY PERSPECTIVE:

Pradeep R. Rai, Carlyne D. Cool, Judy A. C. King, Troy Stevens, Nana Burns, Robert A. Winn, Michael Kasper, and Norbert F. Voelkel

The Cancer Paradigm of Severe Pulmonary Arterial Hypertension

Am. J. Respir. Crit. Care Med. 2008; 178: 558-564. First published online June 12 2008 as doi:10.1164/rccm.200709-1369PP [Abstract] [Full Text] [PDF]  

ARTICLES:

A. Asthma and Allergy:

Harm Maarsingh, Annet B. Zuidhof, I. Sophie T. Bos, Marcel van Duin, Jean-Luc Boucher, Johan Zaagsma, and Herman Meurs

Arginase Inhibition Protects against Allergen-induced Airway Obstruction, Hyperresponsiveness, and Inflammation

Am. J. Respir. Crit. Care Med. 2008; 178: 565-573. First published online June 26 2008 as doi:10.1164/rccm.200710-1588OC [Abstract] [Full Text] [PDF] [Online Supplement]  

Anna Planagumà, Shamsah Kazani, Gautham Marigowda, Oliver Haworth, Thomas J. Mariani, Elliot Israel, Eugene R. Bleecker, Douglas Curran-Everett, Serpil C. Erzurum, William J. Calhoun, Mario Castro, Kian Fan Chung, Benjamin Gaston, Nizar N. Jarjour, William W. Busse, Sally E. Wenzel, and Bruce D. Levy for the NHLBI Severe Asthma Research Program (SARP)

Airway Lipoxin A₄ Generation and Lipoxin A₄ Receptor Expression Are Decreased in Severe Asthma

Am. J. Respir. Crit. Care Med. 2008; 178: 574-582. First published online June 26 2008 as doi:10.1164/rccm.200801-061OC [Abstract] [Full Text] [PDF] [Online Supplement]  

Chun-Hua Wang, Chien-Da Huang, Horng-Chyuan Lin, Kang-Yun Lee, Shu-Min Lin, Chien-Ying Liu, Kuo-Hsiung Huang, Yu-Shien Ko, Kian Fan Chung, and Han-Pin Kuo

Increased Circulating Fibrocytes in Asthma with Chronic Airflow Obstruction

Am. J. Respir. Crit. Care Med. 2008; 178: 583-591. First published online June 26 2008 as doi:10.1164/rccm.200710-1557OC [Abstract] [Full Text] [PDF] [Online Supplement]  

B. Chronic Obstructive Pulmonary Disease:

Deepti Malhotra, Rajesh Thimmulappa, Ana Navas-Acien, Andrew Sandford, Mark Elliott, Anju Singh, Linan Chen, Xiaoxi Zhuang, James Hogg, Peter Pare, Rubin M. Tuder, and Shyam Biswal

Decline in NRF2-regulated Antioxidants in Chronic Obstructive Pulmonary Disease Lungs Due to Loss of Its Positive Regulator, DJ-1

Am. J. Respir. Crit. Care Med. 2008; 178: 592-604. First published online June 12 2008 as doi:10.1164/rccm.200803-380OC [Abstract] [Full Text] [PDF] [Online Supplement]  

C. Critical Care:

Sang-Bum Hong, Yong Huang, Liliana Moreno-Vinasco, Saad Sammani, Jaideep Moitra, Joseph W. Barnard, Shwu-Fan Ma, Tamara Mirzapoiazova, Carrie Evenoski, Ryan R. Reeves, Eddie T. Chiang, Gabriel D. Lang, Aliya N. Husain, Steven M. Dudek, Jeffrey R. Jacobson, Shui Q. Ye, Yves A. Lussier, and Joe G. N. Garcia

Essential Role of Pre–B-Cell Colony Enhancing Factor in Ventilator-induced Lung Injury

Am. J. Respir. Crit. Care Med. 2008; 178: 605-617. First published online July 24 2008 as doi:10.1164/rccm.200712-1822OC [Abstract] [Full Text] [PDF] [Online Supplement]  

Kathleen D. Liu, Joseph Levitt, Hanjing Zhuo, Richard H. Kallet, Sandra Brady, Jay Steingrub, Mark Tidswell, Mark D. Siegel, Graciela Soto, Michael W. Peterson, Mark S. Chesnutt, Charles Phillips, Ann Weinacker, B. Taylor Thompson, Mark D. Eisner, and Michael A. Matthay

Randomized Clinical Trial of Activated Protein C for the Treatment of Acute Lung Injury

Am. J. Respir. Crit. Care Med. 2008; 178: 618-623. First published online June 19 2008 as doi:10.1164/rccm.200803-419OC [Abstract] [Full Text] [PDF] [Online Supplement]  

D. Environmental and Occupational Lung Disease:

Norio Kurumatani and Shinji Kumagai

Mapping the Risk of Mesothelioma Due to Neighborhood Asbestos Exposure

Am. J. Respir. Crit. Care Med. 2008; 178: 624-629. First published online June 12 2008 as doi:10.1164/rccm.200801-063OC [Abstract] [Full Text] [PDF] [Online Supplement]  

E. Pulmonary Infections:

Fred M. Gordin, Mollie P. Roediger, Pierre-Marie Girard, Jens D. Lundgren, Jose M. Miro, Adrian Palfreeman, Maria C. Rodriguez-Barradas, Marcelo J. Wolff, Philippa J. Easterbrook, Kate Clezy, and Leonard N. Slater

Pneumonia in HIV-infected Persons: Increased Risk with Cigarette Smoking and Treatment Interruption

Am. J. Respir. Crit. Care Med. 2008; 178: 630-636. First published online July 10 2008 as doi:10.1164/rccm.200804-617OC [Abstract] [Full Text] [PDF]  

F. Pulmonary Vascular Disease:

Jérôme Le Pavec, Rogério Souza, Philippe Herve, Didier Lebrec, Laurent Savale, Colas Tcherakian, Xavier Jaïs, Azzedine Yaïci, Marc Humbert, Gérald Simonneau, and Olivier Sitbon

Portopulmonary Hypertension: Survival and Prognostic Factors

Am. J. Respir. Crit. Care Med. 2008; 178: 637-643. First published online July 10 2008 as doi:10.1164/rccm.200804-613OC [Abstract] [Full Text] [PDF]  

G. Sleep and Control of Ventilation:

Galia K. Soukhova-O'Hare, Zahoor A. Shah, Zhenmin Lei, Alexander D. Nozdrachev, C. Venkateswara Rao, and David Gozal

Erectile Dysfunction in a Murine Model of Sleep Apnea

Am. J. Respir. Crit. Care Med. 2008; 178: 644-650. First published online June 5 2008 as doi:10.1164/rccm.200801-190OC [Abstract] [Full Text] [PDF]  

CORRESPONDENCE:

Hans L. Rieder

Estimating the Prevalence of Tuberculosis Infection in the United States Population

Am. J. Respir. Crit. Care Med. 2008; 178: 651 [Full Text] [PDF]  

Chi Chiu Leung and Wing Wai Yew

Decline in Prevalence of Latent Tuberculosis Infection: Is the Waning of Tuberculin Reaction a Factor?

Am. J. Respir. Crit. Care Med. 2008; 178: 651-652 [Full Text] [PDF]  

Kamran Khan, Thomas R. Navin, Jeanne M. Courval, Arlene Bierman, Diane E. Bennett, Kenneth G. Castro, and Michael Gardam

Decline in Prevalence of Latent Tuberculosis Infection: Is the Waning of Tuberculin Reaction a Factor?

Am. J. Respir. Crit. Care Med. 2008; 178: 652-653 [Full Text] [PDF]  

Allard E. Dembe

Can Moderate Doses of Vitamin E Protect against Lung Cancer?

Am. J. Respir. Crit. Care Med. 2008; 178: 653 [Full Text] [PDF]  

Christopher G. Slatore, David H. Au, and Emily White

Can Moderate Doses of Vitamin E Protect against Lung Cancer?

Am. J. Respir. Crit. Care Med. 2008; 178: 653-654 [Full Text] [PDF]  

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